For Pets

Ease

Settled bellies, easy digestion, and a calm gut your dog or cat can feel — stirred into the food bowl.

A happy animal starts in the gut. When digestion runs smoothly, everything downstream follows — steady appetite, comfortable bellies, firm and regular stools, and the easy, settled disposition of a companion who simply feels good in their own body. Ease is built for exactly that. It is the formula you reach for when your dog gulps their dinner too fast and grumbles afterward, when a sensitive cat's stomach turns at the slightest change, or when a rich treat, a new bag of food, or the ordinary stress of a vet visit or a thunderstorm leaves the gut unsettled. It is gentle enough to belong in the food bowl every single day, as quiet daily maintenance for an animal whose digestion you simply want to keep running well.

What you are giving is not a sedative and not a quick patch — it is nourishment for the whole digestive terrain. Food-grade botanicals work on different parts of the same system at once: warming the stomach so it empties comfortably, soothing and coating the gut lining, feeding the beneficial microbes that do the real work of digestion, and steadying the nervous, stress-driven side of the gut that turns a tense moment into a turned stomach. Animals carry their stress in their stomachs much as we do — the gut and the nervous system are wired together — so a formula that calms the gut also calms the animal, and a calmer animal digests better still. Ease works that loop from both ends.

Because it is whole-herb food rather than an isolated drug, it supports the body's own digestive intelligence instead of overriding it. You are not forcing a process; you are giving the gut the materials and the comfort it needs to do what it already knows how to do. Owners reach for Ease for the day-to-day: the post-meal settle, the sensitive-stomach companion, the older animal whose digestion has grown a little temperamental, the transition to a new food, and the simple, ongoing goal of a gut that just works — quietly, comfortably, every day.

What it supports in the animal

LiverDigestiveEndocrineImmuneRespiratory

The body systems the herbs in this formula are traditionally understood to nourish — resolved through our knowledge graph, where the classical record and modern biology are read together. Structure and function, never a claim of treatment.

For Pets

$20.00/ 1 oz / 12 g

Small-batch. Dual-extracted where it matters. Made by hand.

How to take it

Wellness dose by body weight — begin with the minimum, adjust as needed: ~1/16 tsp at 5 lbs · ~1/8 tsp at 10 lbs · ~1/4 tsp at 20–30 lbs · ~1/2 tsp at 40–50 lbs, daily, mixed into food.

Whole plant, never isolated

Concentrated extracts of the whole botanical — the way the body recognizes it.

Cited to measured biology

Every action we describe traces to the compound and its measured target.

Structure & function

We describe what an herb nourishes — never a claim to treat disease.

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What you get

What this formula gives you

Supports comfortable, settled digestion after meals — the post-dinner grumble and the gulped-too-fast belly

Nourishes a balanced gut microbiome through real prebiotic fiber, not buzzwords

Soothes and supports the gut lining with gentle demulcent and bitter-tonic herbs working together

Helps steady the stress-and-stomach connection, so an anxious moment is less likely to become an upset gut

Encourages normal motility and orderly stomach emptying through ginger's warming, food-grade action

Gentle and food-grade enough for daily maintenance — supporting an animal whose digestion you simply want to keep running well

How it works

The science of Ease

Not buzzwords — the actual biology of the plants in this formula: their compounds, the targets those compounds are measured to engage, and the systems they nourish.

Ease works across four layers of the digestive system at once, and each layer traces to real compounds in these herbs. Start with the stomach itself. Ginger (Zingiber officinale) is built around the pungent gingerols and shogaols — 6-gingerol and 6-shogaol — and these molecules act directly on the sensory ion channels TRPV1 and TRPA1 that line the gut wall. Engaging those channels is the molecular signature of ginger's warming, motility-promoting, stomach-settling character: it encourages the stomach to empty in an orderly way and helps quiet the queasy, unsettled signaling that follows a too-fast or too-rich meal. The same gingerols touch the eicosanoid enzymes COX-1, COX-2, and 5-lipoxygenase, the body's own machinery for setting inflammatory and comfort tone in tissue — which is why ginger reads, across every herbal tradition that ever used it, as the root that makes a tense gut comfortable.

The second layer is the gut lining and the bitter, bile-and-microbiome axis. Licorice (Glycyrrhiza glabra) is the classic demulcent: its glycyrrhizin and flavonoids (liquiritigenin, glabridin) give it a soothing, coating quality over the digestive mucosa, and its glycyrrhetinic acid engages 11-beta-hydroxysteroid dehydrogenase (HSD11B1 and HSD11B2), the enzymes that govern local cortisol tone — the molecular reason licorice has been the great harmonizer of formulas in Western, Greek-Galenic, Ayurvedic and East Asian practice alike, the herb that unifies and gentles everything around it. Asparagus root (Asparagus cochinchinensis) adds a moistening, yin-tonic counterpoint through its steroidal saponins, beta-sitosterol and rutin, softening any dryness or heat in the system. And dandelion (Taraxacum officinale) brings the bitter principle: a taproot rich in inulin and in luteolin, apigenin and chicoric and chlorogenic acids. The bitterness itself is functional — bitter compounds on the tongue and gut prime digestive secretion and bile flow — while the inulin is a true prebiotic fiber, the food that beneficial gut microbes ferment, which is the foundation of genuine microbiome balance rather than a marketing phrase.

The third and fourth layers are the stress-gut connection and the inflammatory tone of the whole terrain. Gynostemma (Gynostemma pentaphyllum) carries gypenosides and ginsenosides — saponins structurally close to ginseng's — and several of these are measured activators of AMPK, the master cellular energy and metabolic sensor; as a food-grade adaptogen it supports a steady stress response, and because the gut is wired straight to the nervous system, steadying the animal's response to stress directly steadies the gut. Reishi (Ganoderma lucidum) completes the formula with its ganoderic-acid triterpenes and beta-glucans, which support balanced inflammatory and immune signaling (engaging mediators such as STAT3) and help keep the gut's immune tone calm and even. Together these six are not six redundant digestive aids — they are one coordinated approach to the terrain: warm and move the stomach, soothe and coat the lining, feed the microbes, and calm the nervous and inflammatory signaling that ties the whole system together.

The molecules, measured

A formula is a community of compounds. Below are active molecules from the herbs in this blend and the proteins each is measured to engage — the precise points where the plants meet biology. So you see not just that it works, but how.

Dandelion

Taraxacum officinale

Luteolin

PubChem ↗

Measured to act on

Nuclear receptor ROR-gamma

A receptor that helps guide immune cell development and daily metabolic rhythms.

Cytochrome P450 3A4

A major liver enzyme that processes and clears a large share of dietary and plant compounds.

Xanthine dehydrogenase/oxidase

An enzyme that breaks down purines, producing uric acid as a byproduct.

Apigenin

PubChem ↗

Measured to act on

Cytochrome P450 3A4

A major liver enzyme that processes and clears a large share of dietary and plant compounds.

Aromatase

The enzyme that converts androgens into estrogens, balancing the body's hormones.

Amine oxidase [flavin-containing] A

An enzyme that breaks down serotonin and other mood-related brain messengers.

Ginger

Zingiber officinale

6-Gingerol

PubChem ↗

Measured in the lab: binds to Transient receptor potential cation channel subfamily V member 1 · EC50 3.3 µM

Measured to act on

Cytochrome P450 3A4

A major liver enzyme that processes a wide range of compounds the body takes in.

Tyrosyl-DNA phosphodiesterase 1

A repair enzyme that resolves certain DNA damage so the strand can be restored.

Cytochrome P450 2C9

A liver enzyme that helps break down and process many compounds and natural substances.

6-Shogaol

PubChem ↗

Measured in the lab: binds to Cytochrome P450 1A2 · IC50 2.5 µM

Measured to act on

Cytochrome P450 3A4

A major liver enzyme that processes a wide range of compounds the body takes in.

Cytochrome P450 2D6

A liver enzyme that processes many compounds, including some the body forms naturally.

Transient receptor potential cation channel subfamily V member 1

A nerve-ending sensor that responds to heat and to the pungency of chili pepper compounds.

Licorice

Glycyrrhiza glabra

18beta-Glycyrrhetinic acid (enoxolone)

PubChem ↗

Measured in the lab: binds very tightly to 11-beta-hydroxysteroid dehydrogenase type 2 · IC50 1.2 nM

Measured to act on

11-beta-hydroxysteroid dehydrogenase type 1

An enzyme in tissues like fat and liver that activates the stress hormone cortisol.

11-beta-hydroxysteroid dehydrogenase type 2

A kidney enzyme that switches off cortisol, helping the body manage salt and fluid balance.

Protein kinase C eta type

A signaling enzyme involved in skin cell growth and how cells respond to their environment.

Liquiritigenin

PubChem ↗

Measured in the lab: binds very tightly to Estrogen receptor beta · EC50 37 nM

Measured to act on

Estrogen receptor beta

A receptor that reads the hormone estrogen, helping govern reproductive and other tissues.

Tubulin

The building-block protein of the internal scaffolding that gives cells shape and moves their parts.

Asparagus Root

Asparagus cochinchinensis

Diosgenin (steroidal sapogenin aglycone of A. cochinchinensis saponins)

PubChem ↗

Measured to act on

Oxysterol-binding protein 1

A protein that shuttles cholesterol and lipids between compartments inside the cell.

Sarsasapogenin (steroidal sapogenin)

PubChem ↗

Measured in the lab: binds tightly to Solute carrier organic anion transporter family member 1B3 · IC50 105 nM

Measured to act on

Solute carrier organic anion transporter family member 1B3

A liver transporter that draws compounds from the blood into liver cells.

Solute carrier organic anion transporter family member 1B1

A liver transporter that helps usher substances into the liver for processing.

Amyloid-beta precursor protein

A membrane protein in brain cells whose fragments play a role in neural signaling and structure.

Gynostemma

Gynostemma pentaphyllum

Ginsenoside Rb1

PubChem ↗

Measured to act on

AMPK alpha2/beta1/gamma1

The cell's energy sensor, balancing fuel use when reserves run low.

Ginsenoside Rd

PubChem ↗

Measured to act on

AMPK alpha2/beta1/gamma1

The cell's energy sensor, balancing fuel use when reserves run low.

Reishi

Ganoderma lucidum

Ganoderic acid A

PubChem ↗

Measured to act on

11-beta-hydroxysteroid dehydrogenase 1

An enzyme that locally regenerates active cortisol, shaping how tissues respond to the body's stress hormone.

11-beta-hydroxysteroid dehydrogenase type 2

An enzyme that quiets cortisol inside kidney and salt-handling tissues, helping govern fluid and mineral balance.

Aldo-keto reductase family 1 member B1

An enzyme that converts glucose into sorbitol, part of how cells handle sugar.

Ganoderic acid B

PubChem ↗

Measured to act on

Acetylcholinesterase

The enzyme that breaks down acetylcholine, resetting nerve and muscle signals between pulses.

Cholinesterase

A blood enzyme that breaks down acetylcholine and helps clear certain compounds from circulation.

Aldo-keto reductase family 1 member B1

An enzyme that converts glucose into sorbitol, part of how cells handle sugar.

Measured molecular activities drawn from public scientific databases (PubChem, ChEMBL), shown as the characterized chemistry of the plants in this formula — every edge traced to its source record. This describes the molecules, not the product. Structure and function only; these statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

In practice

Who it’s for, and how to use it

Who it’s for

For dogs and cats whose digestion needs day-to-day support: the sensitive-stomach companion, the fast eater who grumbles after meals, the animal transitioning to new food, the older pet whose gut has grown temperamental, and the anxious one who carries tension in their belly. Reach for it as gentle daily maintenance for a gut you want to keep running smoothly, or during the ordinary stresses — travel, a vet visit, a storm, a diet change — that unsettle digestion. Begin at the minimum dose for your animal's weight and adjust as needed. Licorice is included at a small, supportive level, so use it as directed rather than far above the wellness dose; if your animal is pregnant, on prescription medication (especially diuretics, anticoagulants, or NSAIDs), or under treatment for a specific condition, check with your veterinarian first.

How to use it

Stir the wellness dose into food once daily, scaled to body weight — about 1/16 tsp at 5 lbs, 1/8 tsp at 10 lbs, 1/4 tsp at 20-30 lbs, 1/2 tsp at 40-50 lbs. Begin at the minimum for your animal's size and adjust gradually as needed. The powder mixes cleanly into wet food or a little broth, and a calm, consistent daily routine serves the gut better than large occasional amounts.

Measure · Wellness dose by body weight — begin with the minimum, adjust as needed: ~1/16 tsp at 5 lbs · ~1/8 tsp at 10 lbs · ~1/4 tsp at 20–30 lbs · ~1/2 tsp at 40–50 lbs, daily, mixed into food.

What’s inside

Inside: dandelion root, ginger, licorice, asparagus root, gynostemma, and reishi. The combination is deliberate — ginger warms and settles the stomach, dandelion's bitterness and inulin support digestion and feed the microbiome, licorice soothes and harmonizes, asparagus root moistens, gynostemma steadies the stress response, and reishi keeps the gut's immune and inflammatory tone calm. Food-grade herbs, each covering a different part of one system, and gentle enough to belong in the daily bowl.

Structure-and-function support for animal nutrition and vitality. Introduce gradually and watch how your companion responds. Not intended to diagnose, treat, cure, or prevent any disease. If your animal is pregnant, nursing, or on medication, consult your veterinarian first.

Pairs well with

Formulas that share Ease's botanicals

Built from overlapping herbs, these reinforce Easealong the same lines — the shared-botanical kinship our genome engine maps.