For Pets
Mend
For the animal coming home — a quiet rebuilding of strength, appetite, and shine.
Recovery from illness, surgery, or a hard stretch leaves an animal thinner, flatter, slower to eat. Mend meets that animal where it is. Rather than pushing, it offers the steady, food-grade tonics that convalescent traditions have long leaned on to coax back appetite and everyday energy without overwhelming a system that is still finding its feet.
Codonopsis and astragalus carry the load here — both prized in East Asian herbal tradition for rebuilding a depleted constitution gently, the way a slow, nourishing broth does more than a jolt. Reishi works alongside them, lending its calm, restorative character as the animal settles back into its rhythm.
Goji and longan berries round the blend toward replenishment: sweet, palatable, nourishing fruits used for generations to restore an animal that has been running on empty. Licorice ties it together and keeps the whole thing soft on a stomach that may still be tentative.
What it supports in the animal
The body systems the herbs in this formula are traditionally understood to nourish — resolved through our knowledge graph, where the classical record and modern biology are read together. Structure and function, never a claim of treatment.
For Pets
Small-batch. Dual-extracted where it matters. Made by hand.
How to take it
Stir a small amount of the dilute extract or powder into food, scaled to body weight. Start low and build gradually as the animal regains condition.
Whole plant, never isolated
Concentrated extracts of the whole botanical — the way the body recognizes it.
Cited to measured biology
Every action we describe traces to the compound and its measured target.
Structure & function
We describe what an herb nourishes — never a claim to treat disease.
Secure checkout
Encrypted payment and human verification on every order.
What you get
What this formula gives you
Supports the return of appetite and everyday energy
Helps replenish a thin or depleted body
Steadies vitality as strength rebuilds
Gentle and food-grade for a sensitive, recovering stomach
Body-weight-scaled so you can start low and build
How it works
The science of Mend
Not buzzwords — the actual biology of the plants in this formula: their compounds, the targets those compounds are measured to engage, and the systems they nourish.
The botanicals in Mend share one quality: they rebuild rather than stimulate. Codonopsis, often called the gentle cousin of ginseng, is a classic East Asian tonic for the weak, underweight, or slow-to-recover — it supports appetite and steady energy without the heat of stronger roots. Astragalus complements it as one of tradition's foremost vitality roots, valued for restoring an organism worn down by a long depletion.
Reishi adds restorative, calming support as the animal recovers its footing, while goji and longan are long-used nourishing fruits that replenish blood and condition in a depleted body. Licorice harmonizes the blend and soothes digestion — keeping the formula structure-and-function gentle, food-grade, and well suited to a convalescing animal rather than a robust one.
The molecules, measured
A formula is a community of compounds. Below are active molecules from the herbs in this blend and the proteins each is measured to engage — the precise points where the plants meet biology. So you see not just that it works, but how.
Codonopsis pilosula
Syringin
PubChem ↗Measured to act on
An enzyme that makes prostaglandins for everyday housekeeping like stomach lining and blood flow.
An enzyme that breaks down fatty-acid signals involved in blood vessel and inflammation balance.
Atractylenolide I
PubChem ↗Measured to act on
An enzyme that converts fatty acids into messengers of the inflammatory response.
An enzyme that makes prostaglandins for everyday housekeeping like stomach lining and blood flow.
A guardian protein that watches over DNA and helps cells decide when to repair or stop dividing.
Astragalus membranaceus
Formononetin
PubChem ↗Measured in the lab: binds very tightly to Apoptosis regulator Bcl-2 · Ki 10 nM
Measured to act on
A liver enzyme that breaks down many compounds the body takes in.
A protein that helps decide whether a cell continues living or undergoes natural turnover.
An enzyme that edits proteins to manage cellular cleanup and the cell internal scaffolding.
Calycosin
PubChem ↗Measured to act on
A protein that helps organize DNA and acts as an alarm signal during tissue stress.
Ganoderma lucidum
Ganoderic acid A
PubChem ↗Measured to act on
An enzyme that locally regenerates active cortisol, shaping how tissues respond to the body's stress hormone.
An enzyme that quiets cortisol inside kidney and salt-handling tissues, helping govern fluid and mineral balance.
An enzyme that converts glucose into sorbitol, part of how cells handle sugar.
Ganoderic acid B
PubChem ↗Measured to act on
The enzyme that breaks down acetylcholine, resetting nerve and muscle signals between pulses.
A blood enzyme that breaks down acetylcholine and helps clear certain compounds from circulation.
An enzyme that converts glucose into sorbitol, part of how cells handle sugar.
Lycium barbarum
Betaine
PubChem ↗Measured to act on
An enzyme that recycles the amino acid homocysteine back into methionine using betaine.
Scopoletin
PubChem ↗Measured in the lab: binds tightly to Carbonic anhydrase 9 · Ki 960 nM
Measured to act on
An enzyme that helps cells balance acidity by managing carbon dioxide.
Dimocarpus longan
Gallic acid
PubChem ↗Measured in the lab: binds very tightly to Amyloid-beta precursor protein · EC50 1.7 nM
Measured to act on
A mitochondrial enzyme involved in breaking down fatty acids and balancing steroid hormones.
An enzyme that adds sugar tags to cells, helping immune cells find their way through tissue.
An enzyme that edits chemical tags on DNA-packaging proteins to regulate genes.
Ellagic acid
PubChem ↗Measured in the lab: binds very tightly to Amyloid-beta precursor protein · EC50 1.7 nM
Measured to act on
A protein that repairs damaged DNA and helps balance the cell's oxidative state.
A constantly active signaling enzyme involved in cell growth and stress responses.
An enzyme in the liver and red blood cells that helps turn sugar into usable energy.
Glycyrrhiza glabra
18beta-Glycyrrhetinic acid (enoxolone)
PubChem ↗Measured in the lab: binds very tightly to 11-beta-hydroxysteroid dehydrogenase type 2 · IC50 1.2 nM
Measured to act on
An enzyme in tissues like fat and liver that activates the stress hormone cortisol.
A kidney enzyme that switches off cortisol, helping the body manage salt and fluid balance.
A signaling enzyme involved in skin cell growth and how cells respond to their environment.
Liquiritigenin
PubChem ↗Measured in the lab: binds very tightly to Estrogen receptor beta · EC50 37 nM
Measured to act on
A receptor that reads the hormone estrogen, helping govern reproductive and other tissues.
The building-block protein of the internal scaffolding that gives cells shape and moves their parts.
Measured molecular activities drawn from public scientific databases (PubChem, ChEMBL), shown as the characterized chemistry of the plants in this formula — every edge traced to its source record. This describes the molecules, not the product. Structure and function only; these statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.
In practice
Who it’s for, and how to use it
Who it’s for
For dogs, cats, and other companion animals coming back from illness, surgery, or a stretch that left them thin, tired, or off their food. Best for the gentle rebuilding phase, not the acute one.
How to use it
Stir a small amount of the dilute extract or powder into food, scaled to the animal's body weight, starting low. Build gradually as appetite and condition return.
Measure · Stir a small amount of the dilute extract or powder into food, scaled to body weight. Start low and build gradually as the animal regains condition.
What’s inside
Inside you'll find codonopsis and astragalus — the gentle convalescent roots of East Asian tradition — alongside restorative reishi, nourishing goji and longan berries, and a measure of licorice to keep it soft and harmonious for a recovering body.
Structure-and-function support for animal nutrition and vitality. Introduce gradually and watch how your companion responds. Not intended to diagnose, treat, cure, or prevent any disease. If your animal is pregnant, nursing, or on medication, consult your veterinarian first.
Pairs well with
Formulas that share Mend's botanicals
Built from overlapping herbs, these reinforce Mendalong the same lines — the shared-botanical kinship our genome engine maps.