For Pets

Zen

For the animal who startles at thunder, paces before the car ride, or simply lives a little too keyed-up — a daily measure of grounded calm, fed gently into the systems that govern composure.

Some animals carry their nervous system close to the surface. The dog who trembles and hides at the first roll of thunder. The cat who flattens and stops eating the moment the carrier comes out. The young, bright, high-strung companion who never quite settles — pacing, panting, watching the door, unable to switch off even when nothing is wrong. Zen is for that animal. It is a calming, food-grade tonic built to support an even, settled disposition: the kind of grounded composure that lets a body stay present through a storm, a journey, a houseful of guests, or simply an ordinarily over-wired day.

What you are reaching for here is not sedation. A sedated animal is dulled, heavy, switched off — that is not what this is and not what the herbal tradition has ever offered. Zen works the other way around. It nourishes the systems the body itself uses to find steadiness, so that calm arises from within rather than being imposed from outside. The animal stays itself — alert, aware, fully present — but with the volume of its own alarm turned down to something it can live inside. That distinction is the whole point. We are feeding composure, not erasing the animal.

Reach for it in the predictable moments that undo a sensitive animal: the season of summer storms, the long car ride or the trip to a new place, the fireworks evening, the crate, the boarding stay, the new baby or new pet in the house. And reach for it, too, for the animal whose baseline is simply nervous — the constitutionally high-strung disposition that has nothing to do with any single event and everything to do with how that particular creature is wired. Given daily as a quiet measure mixed into food, Zen is meant to build a steadier floor under that animal over time, not just paper over one bad afternoon.

It is gentle enough to live alongside. These are nourishing tonic foods, scaled to body weight and begun at the smallest sensible dose, suitable for dogs and cats and — at properly scaled measure — other companion animals. It asks nothing dramatic of the body. It simply gives the nervous system, the heart, and the body's stress-response machinery the kind of botanical nourishment they recognize and know how to use.

What it supports in the animal

DigestiveEndocrineLiverMusculoskeletalNervous

The body systems the herbs in this formula are traditionally understood to nourish — resolved through our knowledge graph, where the classical record and modern biology are read together. Structure and function, never a claim of treatment.

For Pets

$20.00/ 1 oz / 12 g

Small-batch. Dual-extracted where it matters. Made by hand.

How to take it

Wellness dose by body weight — begin with the minimum: ~1/8 tsp at 10 lbs · ~1/4 tsp at 20–30 lbs · ~1/2 tsp at 40–50 lbs, daily or as needed, mixed into food.

Whole plant, never isolated

Concentrated extracts of the whole botanical — the way the body recognizes it.

Cited to measured biology

Every action we describe traces to the compound and its measured target.

Structure & function

We describe what an herb nourishes — never a claim to treat disease.

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What you get

What this formula gives you

Supports a calm, settled disposition in animals who run high-strung or anxious by nature

Helps a sensitive companion stay grounded through predictable stressors — storms, fireworks, travel, vet visits, boarding, household upheaval

Feeds the body's own stress-response systems so composure builds from within, without dulling or sedating the animal

Nourishes the nervous system and the heart — the systems the tradition links to an even, present temperament

Gentle, food-grade, body-weight-scaled tonic suitable for daily steadying use over time

Supports clarity and a quiet, focused calm rather than agitation, thanks to the lion's mane and dendrobium in the blend

How it works

The science of Zen

Not buzzwords — the actual biology of the plants in this formula: their compounds, the targets those compounds are measured to engage, and the systems they nourish.

Composure is not one organ's job — it is a conversation between several systems, and Zen is composed to feed each side of that conversation rather than to override any of it. The blend's center of gravity is longan (Dimocarpus longan), the honey-sweet dragon-eye fruit that the herbal lineage has reached for across southern China and Southeast Asia precisely to nourish the heart and settle the mind. We use only the aril — the flesh, never the seed or shell — concentrated as a 10:1 extract. Its naturally rich polyphenol fraction (gallic acid, ellagic acid, quercetin, and related flavonoids confirmed against PubChem and ChEMBL records) places longan among the body's recognized dietary antioxidants, the class that supports an animal's own systems for managing everyday oxidative load. In the apothecary's reading it nourishes the heart-blood and, through that center, supports the calm, even baseline the tradition has always linked to a well-fed heart. It is the warm, sweet, steadying note the whole formula is built around — the base that grounds the more active herbs and that makes the experience one of settled steadiness rather than a jolt.

Around that steadying center sit the herbs that speak to the nervous system and the stress-response architecture directly. Lion's Mane (Hericium erinaceus) brings its signature hericenones and erinacines — compound classes verified by name-lookup against PubChem and unique to this mushroom — alongside the beta-glucans that give it its long standing as a nervous-system and digestive tonic; in our and the wider record it supports cognitive and nervous-system wellness in companion animals, the calm-and-clarity axis rather than agitation. Dendrobium (Dendrobium nobile), the prized 'nine immortal herbs' orchid stem, contributes a profoundly moistening, restorative character built on its polysaccharides, and a small bibenzyl fraction — moscatilin and gigantol among them — whose measured molecular targets are telling: gigantol shows binding to calmodulin, the body's master calcium-signaling protein, while moscatilin engages stress-responsive kinases including GSK-3 beta and the JNK and p38 MAP kinase families (all documented in ChEMBL). These are the intracellular pathways through which cells register and modulate stress signals, which is why dendrobium is read as a balancing, settling tonic for the nervous and immune systems rather than a stimulant. It fills and steadies where other herbs push.

The adaptogenic backbone is what keeps that calm from tipping into dullness. Schizandra (Schisandra chinensis), the five-flavor berry, carries its distinctive dibenzocyclooctadiene lignans — schisandrin, schisandrin B, gomisin A and their kin, all confirmed compound identities — which support the liver's natural housekeeping and the body's stress-response systems, helping an animal meet demand and return to baseline without the spike-and-crash of a stimulant. Gynostemma (Gynostemma pentaphyllum), the 'twisting vine' so chemically close to ginseng, supplies gypenosides and ginsenosides (Rb1, Rd and others) whose measured activation of the AMPK energy-sensing complex anchors its standing as a circulatory and stress-resilience tonic; it tones circulation and supports the body's native capacity to find balance under load. Together the five do one coherent thing: longan and dendrobium settle and replenish, lion's mane feeds the nervous system, and schizandra and gynostemma keep the stress-response system supple and even. Structure and function throughout — Zen supplies what the body's own composure machinery is built to use; it does not act against any condition, and it is not a drug.

The molecules, measured

A formula is a community of compounds. Below are active molecules from the herbs in this blend and the proteins each is measured to engage — the precise points where the plants meet biology. So you see not just that it works, but how.

Schizandra

Schisandra chinensis

Schisandrin B (Wuweizisu B)

PubChem ↗

Measured in the lab: binds very tightly to Multidrug resistance-associated protein 1 · IC50 1.25 nM

Measured to act on

Serine/threonine-protein kinase ATR

A guardian enzyme that senses DNA stress and helps coordinate repair.

Serine-protein kinase ATM

A sentinel enzyme that detects DNA breaks and signals the cell to mend them.

DNA-dependent protein kinase catalytic subunit

An enzyme that helps stitch broken DNA strands back together.

Schisandrin C (= Wuweizisu C)

PubChem ↗

Measured to act on

Prostaglandin G/H synthase 2

The enzyme that drives the body's inflammatory response.

Cytochrome P450 3A4

The liver's busiest enzyme for breaking down compounds the body takes in.

Cytochrome P450 3A5

A liver enzyme that helps metabolize and clear many compounds from the body.

Longan Berry

Dimocarpus longan

Gallic acid

PubChem ↗

Measured in the lab: binds very tightly to Amyloid-beta precursor protein · EC50 1.7 nM

Measured to act on

3-hydroxyacyl-CoA dehydrogenase type-2

A mitochondrial enzyme involved in breaking down fatty acids and balancing steroid hormones.

Alpha-(1,3)-fucosyltransferase 7

An enzyme that adds sugar tags to cells, helping immune cells find their way through tissue.

Lysine-specific demethylase 4E

An enzyme that edits chemical tags on DNA-packaging proteins to regulate genes.

Ellagic acid

PubChem ↗

Measured in the lab: binds very tightly to Amyloid-beta precursor protein · EC50 1.7 nM

Measured to act on

DNA repair nuclease/redox regulator APEX1

A protein that repairs damaged DNA and helps balance the cell's oxidative state.

Casein kinase II subunit alpha

A constantly active signaling enzyme involved in cell growth and stress responses.

Pyruvate kinase PKLR

An enzyme in the liver and red blood cells that helps turn sugar into usable energy.

Lion's Mane

Hericium erinaceus

Ergosterol

PubChem ↗

Measured to act on

Protein deacetylase HDAC6

An enzyme that adjusts protein activity and helps the cell clear damaged material.

ATP-dependent translocase ABCB1

A cellular pump that escorts foreign compounds out of cells.

Nitric oxide synthase, inducible

An enzyme immune cells switch on to make nitric oxide, a signaling molecule of the inflammatory response.

Dendrobium

Dendrobium nobile

Moscatilin

PubChem ↗

Measured to act on

Glycogen synthase kinase-3 beta

A versatile signaling enzyme involved in energy storage, cell structure, and growth.

Glycogen synthase kinase-3 beta

A versatile signaling enzyme involved in energy storage, cell structure, and growth.

c-Jun N-terminal kinase

A signaling enzyme that helps cells respond to stress and coordinate their activity.

Gigantol

PubChem ↗

Measured to act on

Calmodulin-1

A small calcium-sensing protein that relays calcium signals throughout the cell.

Calmodulin

A small calcium-sensing protein that relays calcium signals throughout the cell.

RAC-alpha serine/threonine-protein kinase

A central signaling enzyme governing cell growth, survival, and metabolism.

Gynostemma

Gynostemma pentaphyllum

Ginsenoside Rb1

PubChem ↗

Measured to act on

AMPK alpha2/beta1/gamma1

The cell's energy sensor, balancing fuel use when reserves run low.

Ginsenoside Rd

PubChem ↗

Measured to act on

AMPK alpha2/beta1/gamma1

The cell's energy sensor, balancing fuel use when reserves run low.

Measured molecular activities drawn from public scientific databases (PubChem, ChEMBL), shown as the characterized chemistry of the plants in this formula — every edge traced to its source record. This describes the molecules, not the product. Structure and function only; these statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

In practice

Who it’s for, and how to use it

Who it’s for

For the anxious, high-strung, or easily-overwhelmed companion animal — the storm-shy dog, the travel-stressed cat, the young or sensitive pet who never quite winds down. Reach for it ahead of known stressful events (thunderstorm season, fireworks, car trips, vet or grooming visits, boarding, a new home or new family member), or feed it daily as a steadying tonic for an animal whose everyday baseline simply runs too keyed-up. Suitable for dogs and cats, and other companion animals at properly scaled measure. Begin at the smallest dose for the animal's weight and build slowly. As with any new tonic, animals that are pregnant or nursing, or that have an existing health concern or are on medication, should be started only with your veterinarian's guidance.

How to use it

Give as a wellness dose by body weight, mixed into food, beginning with the minimum and adjusting as needed: roughly 1/8 tsp at 10 lbs, 1/4 tsp at 20-30 lbs, and 1/2 tsp at 40-50 lbs, once daily or as needed. For predictable stress (storms, travel, fireworks), it works best fed steadily in the days leading up to the event rather than as a single last-minute dose. Start low, give with a meal, and build gradually — our extracts are potent and a little goes a long way.

Measure · Wellness dose by body weight — begin with the minimum: ~1/8 tsp at 10 lbs · ~1/4 tsp at 20–30 lbs · ~1/2 tsp at 40–50 lbs, daily or as needed, mixed into food.

What’s inside

Inside Zen are gentle tonics chosen for how they work together: longan berry to nourish the heart and settle the mind at the center of the blend, lion's mane to feed the nervous system, dendrobium to fill and steady, and schizandra and gynostemma — the adaptogen pair — to keep the body's stress response even rather than dull. Each is a food-grade extract, scaled for an animal's body, drawn from one unbroken herbal lineage that has reached for these same calming, nourishing plants across cultures for centuries.

Structure-and-function support for animal nutrition and vitality. Introduce gradually and watch how your companion responds. Not intended to diagnose, treat, cure, or prevent any disease. If your animal is pregnant, nursing, or on medication, consult your veterinarian first.

Pairs well with

Formulas that share Zen's botanicals

Built from overlapping herbs, these reinforce Zenalong the same lines — the shared-botanical kinship our genome engine maps.