For Pets/Shield

For Pets

Shield

Daily immune nourishment for the animal you love — functional mushrooms, gentle enough for everyday food, built to keep their natural defenses well-supplied.

Your animal's body already carries a standing intelligence for defense — a network of surveillance cells that recognizes what belongs and what doesn't, and works quietly, every day, to keep them resilient. Immunity is not a remedy you reach for when something is wrong. It is a daily food for that native intelligence: a small spoonful stirred into the bowl that keeps the systems of recognition, balance, and renewal well-nourished, season after season. This is what the great fungal tonics have always been for — not a spike, not a fix, but a steady reserve of vitality the body draws on at its own pace.

What makes this formula worth reaching for is its completeness. Rather than lean on a single mushroom, we built Immunity from the full set — reishi, cordyceps, lion's mane, chaga, turkey tail, and agaricus blazei —, the same full-spectrum blend as our human formula, simply rendered at pet-safe concentrations. Each mushroom carries the family of compounds the body recognizes as familiar, and each adds a distinct strength: deep immune tone, antioxidant density, stamina and oxygen-use, nervous and gut-brain support, and prebiotic nourishment for the gut where so much of immune education quietly happens. Together they cover more of the body's terrain than any one mushroom could alone.

You would reach for it for the healthy animal you simply want to keep healthy — the dog who travels and meets new dogs, the senior cat whose vitality you want to hold steady, the working or sporting animal whose body is asked for more, the bird or horse whose daily resilience you'd like well-supplied. It is gentle by design: food-grade culinary mushrooms, prepared as dilute hot-water extracts, scaled down to the smallest sensible dose and built up gradually. It is daily maintenance, not drama — the kind of quiet, steady support a body recognizes and uses.

And because it is grounded in the same fungal chemistry across all three of our kingdoms — People, Pets, and Plants — you can trust that what nourishes your own resilience is the same lineage nourishing your animal's, scaled with care for their smaller body and different physiology.

What it supports in the animal

DigestiveImmuneEndocrineLiverNervous

The body systems the herbs in this formula are traditionally understood to nourish — resolved through our knowledge graph, where the classical record and modern biology are read together. Structure and function, never a claim of treatment.

For Pets

$20.00/ 1 oz / 12 g

Small-batch. Dual-extracted where it matters. Made by hand.

How to take it

Wellness dose by body weight — begin with the minimum, adjust as needed: ~1/16 tsp at 5 lbs · ~1/8 tsp at 10 lbs · ~1/4 tsp at 20–30 lbs · ~1/2 tsp at 40–50 lbs, daily, mixed into food.

Whole plant, never isolated

Concentrated extracts of the whole botanical — the way the body recognizes it.

Cited to measured biology

Every action we describe traces to the compound and its measured target.

Structure & function

We describe what an herb nourishes — never a claim to treat disease.

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What you get

What this formula gives you

Keeps your animal's natural immune defenses well-nourished and well-regulated, every day

Supplies a dense, full-spectrum antioxidant reserve (melanin, polyphenols, triterpenes) to support cellular resilience against everyday oxidative stress

Nourishes the gut terrain with prebiotic fungal polysaccharides — the foundation of immune and metabolic balance

Supports steady energy, stamina, and recovery through cordyceps' role in the body's own cellular energy production

Tones the nervous and gut-brain terrain via lion's mane, beyond immune support alone

Gentle, food-grade, and pet-safe by design — daily maintenance you can stir into the bowl without drama

How it works

The science of Shield

Not buzzwords — the actual biology of the plants in this formula: their compounds, the targets those compounds are measured to engage, and the systems they nourish.

The throughline of this formula is one of the most elegant facts in all of botanical medicine: the body recognizes mushrooms. Every one of these six is built, at the level of its cell wall, from beta-glucans — long, branched chains of glucose woven into a molecular architecture the mammalian body has been reading for as long as animals have lived and eaten among fungi. The innate immune system carries receptors shaped to recognize precisely these beta-glucan patterns; when a sentinel cell meets them, the body's own machinery of recognition is engaged and toned. This is the meaning of immunomodulation in the strict structure/function sense — the mushroom does not act upon the body or push its defenses in any single direction. It presents a familiar pattern, and the body's own immune intelligence reads it as information and uses it to support its natural, self-regulating balance. Turkey tail concentrates this into its renowned protein-bound polysaccharides (the PSP and PSK fractions), and agaricus blazei carries one of the densest beta-glucan reserves found anywhere in the fungal kingdom — which is why both are prepared as hot-water extracts, the form in which these water-soluble polysaccharides lift cleanly into the body's reach.

On top of that shared immune foundation, each mushroom contributes a distinct second signature, and it is the layering of these that makes the blend more complete than any one. Reishi adds its triterpenes — the bitter, oxygenated ganoderic acids that engage targets in inflammatory and stress signaling (including the STAT3 node in our molecular data) and are traditionally tied to liver support and a grounded, composed nervous tone — placing reishi at the intersection of immune resilience and a steady stress response. Chaga brings an exceptionally concentrated antioxidant fraction: melanin, a broad spectrum of polyphenols, and triterpenes including betulinic acid drawn from its birch host, compound classes that support the body's own cellular defenses against everyday oxidative stress and help maintain a normal inflammatory balance. Turkey tail's polyphenols echo that antioxidant support, while its fibrous, fermentable polysaccharides act as a prebiotic substrate — nourishment for the gut's microbial community, the foundation from which so much immune and metabolic poise arises.

The remaining two reach beyond defense into vitality and the nervous system. Cordyceps is cultivated for its nucleosides — cordycepin and adenosine — and adenosine is the same nucleoside the body builds into ATP, the molecule every cell uses as energy currency, and signals through its own adenosine receptors; the established interest in cordyceps centers on how its profile supports the body's own healthy production and use of cellular energy and its natural use of oxygen during exertion, which is why it is the stamina and recovery mushroom. Lion's mane carries two compound families found almost nowhere else — the hericenones and erinacines — long studied for their relationship with nerve growth factor (NGF), one of the body's own neurotrophic signals through which the nervous system maintains and renews its architecture; alongside its own beta-glucans, this extends the formula's reach to the brain-gut axis, where nervous and digestive systems are in constant conversation. The result is a single blend that nourishes immune, antioxidant, energetic, digestive, and nervous terrain at once — every effect traceable to a real compound in a real mushroom, feeding the systems by which the body governs itself rather than acting against any condition.

The molecules, measured

A formula is a community of compounds. Below are active molecules from the herbs in this blend and the proteins each is measured to engage — the precise points where the plants meet biology. So you see not just that it works, but how.

Reishi

Ganoderma lucidum

Ganoderic acid A

PubChem ↗

Measured to act on

11-beta-hydroxysteroid dehydrogenase 1

An enzyme that locally regenerates active cortisol, shaping how tissues respond to the body's stress hormone.

11-beta-hydroxysteroid dehydrogenase type 2

An enzyme that quiets cortisol inside kidney and salt-handling tissues, helping govern fluid and mineral balance.

Aldo-keto reductase family 1 member B1

An enzyme that converts glucose into sorbitol, part of how cells handle sugar.

Ganoderic acid B

PubChem ↗

Measured to act on

Acetylcholinesterase

The enzyme that breaks down acetylcholine, resetting nerve and muscle signals between pulses.

Cholinesterase

A blood enzyme that breaks down acetylcholine and helps clear certain compounds from circulation.

Aldo-keto reductase family 1 member B1

An enzyme that converts glucose into sorbitol, part of how cells handle sugar.

Cordyceps

Cordyceps militaris

Cordycepin (3'-deoxyadenosine)

PubChem ↗

Measured in the lab: binds to Adenosine receptor A1 · Ki 7.12 µM

Measured to act on

Adenosine receptor A1

A receptor for adenosine that helps calm cellular activity and signaling.

Tyrosyl-DNA phosphodiesterase 1

A repair enzyme that clears certain damage points so DNA can be mended.

Pentostatin (2'-deoxycoformycin)

PubChem ↗

Measured in the lab: binds very tightly to Adenosine deaminase · Ki 1 nM

Measured to act on

Adenosine deaminase

An enzyme that breaks down adenosine, part of how cells recycle their building blocks.

Lion's Mane

Hericium erinaceus

Ergosterol

PubChem ↗

Measured to act on

Protein deacetylase HDAC6

An enzyme that adjusts protein activity and helps the cell clear damaged material.

ATP-dependent translocase ABCB1

A cellular pump that escorts foreign compounds out of cells.

Nitric oxide synthase, inducible

An enzyme immune cells switch on to make nitric oxide, a signaling molecule of the inflammatory response.

Chaga

Inonotus obliquus

Betulinic acid

PubChem ↗

Measured in the lab: binds tightly to Albumin · Kd 593 nM

Measured to act on

Nuclear receptor ROR-gamma

A receptor inside cells that helps direct immune cell development and daily body rhythms.

5'-nucleotidase

An enzyme that recycles the building blocks of DNA and cellular energy molecules.

DNA polymerase beta

An enzyme that helps repair and copy DNA to keep the genetic code intact.

Protocatechuic acid

PubChem ↗

Measured in the lab: binds tightly to Carbonic anhydrase 2 · Ki 470 nM

Measured to act on

Carbonic anhydrase 2

An enzyme that balances carbon dioxide and acidity throughout the body's fluids.

Carbonic anhydrase 1

An enzyme that helps manage carbon dioxide and acid-base balance in the blood.

3-dehydroquinate synthase

A bacterial enzyme in a pathway plants and microbes use that humans lack entirely.

Turkey Tail

Trametes versicolor

Ergosterol

PubChem ↗

Measured to act on

Nitric oxide synthase, inducible

An enzyme that produces nitric oxide as part of the immune and inflammatory response.

UDP-glucuronosyltransferase 1A1

A liver enzyme that attaches sugar groups to compounds so the body can clear them.

Ergosterol peroxide

PubChem ↗

Measured in the lab: binds to Nitric oxide synthase, inducible · IC50 6.3 µM

Measured to act on

Aldo-keto reductase family 1 member B1

An enzyme that converts glucose into sorbitol, part of how cells handle sugar.

Nitric oxide synthase, inducible

An enzyme that produces nitric oxide as part of the immune and inflammatory response.

Bile acid receptor

A receptor that senses bile acids and helps govern fat, cholesterol, and bile balance.

Agaricus Blazei

Agaricus blazei Murill

Ergosterol

PubChem ↗

Measured to act on

Nitric oxide synthase, inducible

An enzyme immune cells switch on to make nitric oxide, a signaling molecule of the inflammatory response.

UDP-glucuronosyltransferase 1A1

A liver enzyme that tags compounds with sugar so the body can clear them.

Solute carrier organic anion transporter family member 1B1

A liver transporter that pulls compounds from the blood into liver cells for processing.

Ergosterol peroxide (5,8-epidioxy-ergosta-6,22-dien-3-ol)

PubChem ↗

Measured to act on

Nitric oxide synthase, inducible

An enzyme immune cells switch on to make nitric oxide, a signaling molecule of the inflammatory response.

Aldo-keto reductase family 1 member B1

An enzyme that converts excess glucose into sorbitol, part of how cells handle sugar.

Bile acid receptor

A sensor that reads bile acid levels and helps govern fat and cholesterol balance.

Measured molecular activities drawn from public scientific databases (PubChem, ChEMBL), shown as the characterized chemistry of the plants in this formula — every edge traced to its source record. This describes the molecules, not the product. Structure and function only; these statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

In practice

Who it’s for, and how to use it

Who it’s for

For the healthy companion animal whose vitality you want to keep steady — dogs and cats first, with the same gentle blend scaled for birds and horses. Reach for it for the traveler who meets new animals, the senior whose resilience you want to hold, the working or sporting animal asked for more, or simply any animal you'd like to keep well-supplied through the changing seasons. It is daily maintenance for a body that is already well, not a remedy for one that is unwell — and as with any immune-active food, animals on immunosuppressive medication, with autoimmune conditions, or with significant kidney or liver concerns (chaga is naturally high in oxalates) should be introduced only with veterinary guidance. Start at the smallest dose and build gradually.

How to use it

A wellness dose scaled to body weight, stirred into food once daily — begin with the minimum and adjust as needed: about 1/16 tsp at 5 lbs, 1/8 tsp at 10 lbs, 1/4 tsp at 20-30 lbs, 1/2 tsp at 40-50 lbs. Start low, build gradually over days, and give with a meal. The extract is genuinely potent, so a little goes a long way.

Measure · Wellness dose by body weight — begin with the minimum, adjust as needed: ~1/16 tsp at 5 lbs · ~1/8 tsp at 10 lbs · ~1/4 tsp at 20–30 lbs · ~1/2 tsp at 40–50 lbs, daily, mixed into food.

What’s inside

Inside: functional mushrooms — reishi, cordyceps, lion's mane, chaga, turkey tail, and agaricus blazei — each a food-grade 10:1 hot-water extract of the fruiting body. We chose this combination because each carries the beta-glucans the body recognizes while adding a strength the others don't: reishi's grounding triterpenes, chaga's antioxidant melanin and polyphenols, turkey tail's prebiotic protein-bound polysaccharides, cordyceps' energy nucleosides, lion's mane's nerve-supporting hericenones and erinacines, and agaricus' exceptionally dense immune polysaccharides. The same complete blend as our human formula, simply rendered gentle for the animal you love.

Structure-and-function support for animal nutrition and vitality. Introduce gradually and watch how your companion responds. Not intended to diagnose, treat, cure, or prevent any disease. If your animal is pregnant, nursing, or on medication, consult your veterinarian first.

Pairs well with

Formulas that share Shield's botanicals

Built from overlapping herbs, these reinforce Shieldalong the same lines — the shared-botanical kinship our genome engine maps.