For People
Frame
Four deep roots and barks for the architecture you stand on — bone, tendon, and a frame built to last.
Frame is for the part of you that holds everything else up. Not the surface, not the show — the scaffolding. Bone. Tendon. The bands of sinew that bind muscle to joint. The deep structural integrity that lets a body bend without breaking and carry load year after year. This is a formula for that frame: four of the most grounded, mineral-rich roots and barks in the botanical world, drawn together to nourish the body's structural foundation.
Where lighter herbs work at the surface, these four work at the root — literally. Eucommia bark, prepared rehmannia root, he shou wu, and cistanche are the deep-reserve tonics of the classical tradition: dense, slow, building herbs that the body recognizes as raw material. They don't push the body. They feed the systems that lay down and maintain structure — the connective tissue, the skeletal framework, the resilient bands that keep a joint stable through a lifetime of movement.
Use Frame when you want to invest in the long structure of the body rather than chase a quick lift. It is for the climber, the lifter, the gardener on their knees in spring soil, the person who simply intends to move well for decades. Steady, daily nourishment for the architecture you stand on — so the frame stays strong, supple, and ready for load.
This is structure-and-function nourishment in the truest sense: we feed the body's own building systems and let the body do the building. Frame supports a strong structural foundation. This product is not intended to diagnose, treat, cure, or prevent any disease — it is food for the framework that carries you.
What it supports in the body
The body systems the herbs in this formula are traditionally understood to nourish — resolved through our knowledge graph, where the classical record and modern biology are read together. Structure and function, never a claim of treatment.
For People
Small-batch. Dual-extracted where it matters. Made by hand.
How to take it
1/4 tsp (up to 1 tsp) of extract powder in hot water, tea, coffee, a smoothie, or food, once daily. Begin with light doses — our extracts are very potent.
What you get
What this formula gives you
Nourishes the body's structural foundation — bone, tendon, and the connective tissue that binds the frame together
Supports strong, supple sinew and the resilient bands that keep joints stable under load
Feeds the deep-reserve systems with dense, mineral-rich roots the body recognizes as raw material
Builds slowly and steadily — a long-game tonic for structural strength
Backed by four convergent botanicals whose key compounds are identified, structure-verified, and traditionally trusted for the frame
Grounding and steadying — a warm, rooted addition to a daily ritual for anyone investing in how well they'll move for years to come
How it works
The science of Frame
Not buzzwords — the actual biology of the plants in this formula: their compounds, the targets those compounds are measured to engage, and the systems they nourish.
These four herbs share a lineage. In the classical Chinese system they are the great tonics of the deep reserve — the Kidney and Jing herbs traditionally held to govern bone, marrow, and the sinews. Eucommia bark (Du Zhong) was the foremost herb for the back, the knees, and the binding of tendon to bone. Prepared rehmannia (Shu Di Huang) was the dense, blood-and-essence builder that supplied the raw substance. He shou wu and cistanche were the slow restorative roots of longevity practice. Frame is not a modern invention — it is one of the oldest structural ideas in herbalism, four convergent roots reached for again and again when the frame itself needed feeding.
When we look at these herbs through a measured molecular lens, the picture is coherent. Eucommia bark is rich in chlorogenic acid and quercetin — polyphenols whose measured molecular interactions (catalogued against defined human targets in the ChEMBL bioactivity database) place them squarely among the antioxidant, connective-tissue-supportive compounds. Cistanche carries echinacoside and acteoside (verbascoside), among the most-studied phenylethanoid glycosides in the plant kingdom, with measured activity against specific defined targets. These are not vague 'actives' — they are identified molecules with verified structures and recorded interactions, which is why this lineage has been trusted for so long.
Across cultures the conclusion was the same one, reached independently. The Greco-Galenic tradition prized the warm, dense, grounding roots for what it called the body's solid parts. African and Western root practice turned to deep barks and rhizomes for endurance and the strength to carry weight. The Chinese named it precisely — bone, sinew, marrow, the lower back and knees. One lineage, many tongues, all pointing at the same truth: the body's structure is built from rich, mineral-dense, deeply nourishing roots, taken slowly and consistently. Frame carries that whole inheritance in a single daily measure.
The molecules, measured
A formula is a community of compounds. Below are active molecules from the herbs in this blend and the proteins each is measured to engage — the precise points where the plants meet biology. So you see not just that it works, but how.
Eucommia ulmoides
Chlorogenic acid
PubChem ↗Measured to act on
A viral enzyme HIV uses to insert its genetic material into a host cell's DNA.
An enzyme that dials down insulin and growth signaling by removing phosphate tags.
An enzyme that converts glucose into sorbitol as part of cellular sugar handling.
Quercetin
PubChem ↗Measured to act on
A structural protein that stabilizes the internal scaffolding of nerve cells.
An enzyme that converts excess glucose into sorbitol, part of how cells handle sugar.
A liver-type enzyme that processes hormones and environmental compounds.
Rehmannia glutinosa
Acteoside (Verbascoside)
PubChem ↗Measured to act on
A family of signaling enzymes that relay messages controlling cell growth and activity.
Aucubin
PubChem ↗Measured to act on
An enzyme that makes prostaglandins for everyday housekeeping like stomach lining and blood flow.
The enzyme that drives the body's inflammatory response by producing prostaglandins.
The receptor through which estrogen signals, governing many reproductive and tissue functions.
Polygonum multiflorum
Emodin
PubChem ↗Measured to act on
A constantly active signaling enzyme involved in cell growth and stress responses.
A regulatory enzyme that removes phosphate tags involved in cell signaling and movement.
An enzyme that converts glucose into sorbitol as part of cellular sugar handling.
Physcion (Parietin)
PubChem ↗Measured to act on
An enzyme released by immune cells that helps break down debris during the inflammatory response.
An enzyme that helps keep cells in antioxidant balance against oxidative stress.
An antioxidant enzyme that protects the cell's energy factories from oxidative stress.
Cistanche deserticola
Echinacoside
PubChem ↗Measured to act on
The enzyme that makes melanin, the pigment that gives skin and hair their color.
Acteoside / Verbascoside
PubChem ↗Measured to act on
An enzyme in brain cells that cuts certain membrane proteins as part of normal cellular processing.
An enzyme that processes the amino acid arginine, governing nitrogen handling within cells.
A signaling enzyme that relays messages inside cells, influencing growth and communication.
Measured molecular activities drawn from public scientific databases (PubChem, ChEMBL), shown as the characterized chemistry of the plants in this formula — every edge traced to its source record. This describes the molecules, not the product. Structure and function only; these statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.
In practice
Who it’s for, and how to use it
Who it’s for
Frame is for any body that asks a lot of its structure and intends to keep asking for years — the lifter, the climber, the runner, the gardener, the tradesperson on their feet all day, the person rebuilding strength patiently, and anyone who simply wants to move well into the long arc of their life. It is for those who would rather feed the foundation than chase the surface. As a deep, building tonic it suits steady daily use over time. If you are pregnant, nursing, or working alongside another regimen, bring Frame into the conversation thoughtfully — these are potent roots, and a little goes a long way.
How to use it
Start light — these extracts are very potent. Take 1/4 teaspoon (working up to 1 teaspoon as you settle in) of the extract powder once daily, stirred into hot water, tea, coffee, a smoothie, or simply mixed into food. Frame is a building tonic, so its gift is in the rhythm: taken consistently, day after day, it gives the body steady raw material to work with. A warm cup in the morning or with a meal makes an easy, grounding ritual. One 1 oz / 12 g jar is a generous daily supply.
Measure · 1/4 tsp (up to 1 tsp) of extract powder in hot water, tea, coffee, a smoothie, or food, once daily. Begin with light doses — our extracts are very potent.
What’s inside
Inside Frame: four deep roots and barks — eucommia bark, prepared rehmannia root, he shou wu, and cistanche — in equal measure. These are the structural tonics of the classical lineage, chosen for one purpose and nothing extra. The most pristine herbs on earth.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Introduce one formula at a time and notice how the body responds; if you are pregnant, nursing, or on a prescription, know the interaction before you begin.