For Plants/Solstice

For Plants

Solstice

Help your plants hold their ground when the cold comes in.

Solstice is built for the turn of the season — the weeks when daylight shortens, the first frosts arrive, and a plant's task shifts from pushing growth to holding what it has. It supports the natural process of hardening off, helping tissues firm and prepare rather than stay soft and vulnerable to cold.

Through deep cold and dormancy, it acts as a steadying presence in the root zone and on the leaf. The adaptogenic roots at its heart — eleuthero and rhodiola among them — come from plants that thrive where winters are brutal, lending the kind of stress-tempered character a garden needs when conditions get extreme.

As warmth returns, plants carried through dormancy with their reserves protected are better positioned to wake with vigor. Solstice is the companion for the resting season — quiet support for the part of the year when survival is the work.

For Plants

$20.00/ 1 oz / 12 g

Small-batch. Dual-extracted where it matters. Made by hand.

How to take it

Dilute 1/8 to 1/4 tsp per gallon of water. Apply as a foliar feed or soil drench as temperatures begin to drop and through the dormant season.

Whole plant, never isolated

Concentrated extracts of the whole botanical — the way the body recognizes it.

Cited to measured biology

Every action we describe traces to the compound and its measured target.

Structure & function

We describe what an herb nourishes — never a claim to treat disease.

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What you get

What this formula gives you

Supports natural hardening-off ahead of frost

Helps plants stay steady through cold snaps

Encourages reserve-building going into dormancy

Draws on botanicals proven hardy in the harshest winters

Positions plants to wake with vigor in spring

How it works

The science of Solstice

Not buzzwords — the actual biology of the plants in this formula: their compounds, the targets those compounds are measured to engage, and the systems they nourish.

The botanicals in Solstice are defined by where they come from. Eleuthero (Siberian ginseng) and rhodiola are cold-climate, high-stress adaptogens — rhodiola grows on exposed arctic and alpine ground, eleuthero across the Siberian taiga. In their own physiology these plants are masters of surviving cold and scarcity, and that hardy, stress-tempered character is what makes them a fitting biostimulant base for a plant facing the same conditions.

Schizandra, a hardy Manchurian vine, and northern astragalus add astringent, root-strengthening character associated in East Asian agronomic tradition with consolidation and reserve-building, while eucommia — a cold-tolerant hardy tree bark — speaks to woody structure and resilience. Warming ginger rounds the blend. Together they support a plant's own hardening and dormancy processes; this is structure-and-function support for resilience, not a cure or a guarantee against frost.

The molecules, measured

A formula is a community of compounds. Below are active molecules from the herbs in this blend and the proteins each is measured to engage — the precise points where the plants meet biology. So you see not just that it works, but how.

Eleuthero

Eleutherococcus senticosus

Eleutheroside B (Syringin)

PubChem ↗

Measured to act on

Prostaglandin G/H synthase 1

An enzyme that makes prostaglandins for everyday upkeep like protecting the stomach lining.

Bifunctional epoxide hydrolase 2

An enzyme that breaks down fatty-acid signals involved in blood vessel tone and inflammation.

Measured to act on

Transient receptor potential cation channel subfamily M member 8

The sensory channel that detects cold and the cooling feel of menthol.

Vitamin D3 receptor

The receptor through which vitamin D guides calcium balance and gene activity.

Serine/threonine-protein kinase PLK1

A signaling enzyme that helps coordinate cell division.

Rhodiola

Rhodiola rosea

Salidroside

PubChem ↗

Measured in the lab: binds tightly to Amine oxidase [flavin-containing] B · IC50 810 nM

Measured to act on

Amine oxidase [flavin-containing] B

An enzyme that breaks down messenger chemicals like dopamine in the nervous system.

Prostaglandin G/H synthase 1

An enzyme that makes prostaglandins for everyday upkeep like protecting the stomach lining.

Ribonuclease HI

An enzyme that cuts RNA when it is paired with DNA, part of normal genetic housekeeping.

Tyrosol (p-Tyrosol)

PubChem ↗

Measured in the lab: binds tightly to Beta-carbonic anhydrase 1 · Ki 850 nM

Measured to act on

Carbonic anhydrase 1

An enzyme that balances carbon dioxide and acidity, abundant in red blood cells.

Carbonic anhydrase 2

A fast enzyme that balances carbon dioxide and acidity throughout the body.

Hepatocyte growth factor receptor

A receptor that receives growth signals guiding cell movement, repair, and renewal.

Schizandra

Schisandra chinensis

Schisandrin B (Wuweizisu B)

PubChem ↗

Measured in the lab: binds very tightly to Multidrug resistance-associated protein 1 · IC50 1.25 nM

Measured to act on

Serine/threonine-protein kinase ATR

A guardian enzyme that senses DNA stress and helps coordinate repair.

Serine-protein kinase ATM

A sentinel enzyme that detects DNA breaks and signals the cell to mend them.

DNA-dependent protein kinase catalytic subunit

An enzyme that helps stitch broken DNA strands back together.

Schisandrin C (= Wuweizisu C)

PubChem ↗

Measured to act on

Prostaglandin G/H synthase 2

The enzyme that drives the body's inflammatory response.

Cytochrome P450 3A4

The liver's busiest enzyme for breaking down compounds the body takes in.

Cytochrome P450 3A5

A liver enzyme that helps metabolize and clear many compounds from the body.

Astragalus

Astragalus membranaceus

Formononetin

PubChem ↗

Measured in the lab: binds very tightly to Apoptosis regulator Bcl-2 · Ki 10 nM

Measured to act on

Cytochrome P450 2C9

A liver enzyme that breaks down many compounds the body takes in.

Apoptosis regulator Bcl-2

A protein that helps decide whether a cell continues living or undergoes natural turnover.

Protein deacetylase HDAC6

An enzyme that edits proteins to manage cellular cleanup and the cell internal scaffolding.

Calycosin

PubChem ↗

Measured to act on

High mobility group protein B1

A protein that helps organize DNA and acts as an alarm signal during tissue stress.

Eucommia

Eucommia ulmoides

Chlorogenic acid

PubChem ↗

Measured in the lab: binds very tightly to Tyrosine-protein phosphatase non-receptor type 1 · IC50 100 nM

Measured to act on

HIV-1 integrase

A viral enzyme HIV uses to insert its genetic material into a host cell's DNA.

Tyrosine-protein phosphatase non-receptor type 1

An enzyme that dials down insulin and growth signaling by removing phosphate tags.

Aldo-keto reductase family 1 member B1

An enzyme that converts glucose into sorbitol as part of cellular sugar handling.

Quercetin

PubChem ↗

Measured in the lab: binds very tightly to Amine oxidase [flavin-containing] A · IC50 10 nM

Measured to act on

Microtubule-associated protein tau

A structural protein that stabilizes the internal scaffolding of nerve cells.

Aldo-keto reductase family 1 member B1

An enzyme that converts excess glucose into sorbitol, part of how cells handle sugar.

Cytochrome P450 1B1

A liver-type enzyme that processes hormones and environmental compounds.

Ginger

Zingiber officinale

6-Gingerol

PubChem ↗

Measured in the lab: binds to Transient receptor potential cation channel subfamily V member 1 · EC50 3.3 µM

Measured to act on

Cytochrome P450 3A4

A major liver enzyme that processes a wide range of compounds the body takes in.

Tyrosyl-DNA phosphodiesterase 1

A repair enzyme that resolves certain DNA damage so the strand can be restored.

Cytochrome P450 2C9

A liver enzyme that helps break down and process many compounds and natural substances.

6-Shogaol

PubChem ↗

Measured in the lab: binds to Cytochrome P450 1A2 · IC50 2.5 µM

Measured to act on

Cytochrome P450 3A4

A major liver enzyme that processes a wide range of compounds the body takes in.

Cytochrome P450 2D6

A liver enzyme that processes many compounds, including some the body forms naturally.

Transient receptor potential cation channel subfamily V member 1

A nerve-ending sensor that responds to heat and to the pungency of chili pepper compounds.

Measured molecular activities drawn from public scientific databases (PubChem, ChEMBL), shown as the characterized chemistry of the plants in this formula — every edge traced to its source record. This describes the molecules, not the product. Structure and function only; these statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

In practice

Who it’s for, and how to use it

Who it’s for

For gardeners and growers preparing perennials, shrubs, and overwintering crops for the cold season. Ideal for anyone in a frost-prone climate who wants to give plants steadying support through dormancy.

How to use it

Dilute 1/8 to 1/4 tsp per gallon and apply as a foliar feed or soil drench as temperatures begin to fall, repeating through the dormant months to support plants as they rest.

Measure · Dilute 1/8 to 1/4 tsp per gallon of water. Apply as a foliar feed or soil drench as temperatures begin to drop and through the dormant season.

What’s inside

Inside you'll find cold-country botanicals chosen for their winter character: Siberian eleuthero and high-altitude rhodiola, hardy Manchurian schizandra, northern astragalus, resilient eucommia bark, and warming ginger — gathered from the places where plants have always known how to survive the cold.

For agricultural and horticultural use. Supports plant growth, vigor, and resilience — not a claim of any effect on human or animal health.

Pairs well with

Formulas that share Solstice's botanicals

Built from overlapping herbs, these reinforce Solsticealong the same lines — the shared-botanical kinship our genome engine maps.